{"doi":"10.1002/anie.201302805","title":"Palladium‐Catalyzed Asymmetric Construction of Vicinal All‐Carbon Quaternary Stereocenters and its Application to the Synthesis of Cyclotryptamine Alkaloids","abstract":null,"journal":"Angewandte Chemie International Edition","year":2013,"id":685625,"datarank":0.7603356303330349,"base_score":5.0689042022202315,"endowment":5.0689042022202315,"self_citation_contribution":0.7603356303330349,"citation_network_contribution":0.0,"self_endowment_contribution":0.7603356303330349,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":158,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1373345,"name":"Maksim Osipov","orcid":"0009-0007-3129-3183","position":1,"is_corresponding":false},{"id":1791276,"name":"Barry M. Trost","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Palladium‐Catalyzed Asymmetric Construction of Vicinal All‐Carbon Quaternary Stereocenters and its Application to the Synthesis of Cyclotryptamine Alkaloids","abstract":"A twofold Pd-DAAA Pd-catalyzed decarboxylative allylic alkylation (see scheme) was used to construct two vicinal all-carbon quaternary stereocenters (marked in red) in a diastereo- and enantioselective fashion. The products of the Pd-DAAA were further elaborated to complete the formal syntheses of cyclotryptamine alkaloids. The twofold Pd-catalyzed transformation proceeds through an initial matched allylation followed by a second mismatched allylation to deliver the desired product.","is_dataset_classified":null,"base_score":5.0689042022202315,"endowment":5.0689042022202315,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23824625","pmcid":"PMC3825681","openalex_id":"https://openalex.org/W2102790079","authors":[],"funders":[{"funder_name":"NIGMS NIH HHS","grant_id":"GM 033049","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM033049","title":null}],"total_grants":2,"fwci":9.9996,"citation_percentile":0.98826083,"influential_citations":0,"citation_trend":[{"year":2012,"count":1},{"year":2013,"count":5},{"year":2014,"count":21},{"year":2015,"count":20},{"year":2016,"count":17},{"year":2017,"count":17},{"year":2018,"count":18},{"year":2019,"count":6},{"year":2020,"count":10},{"year":2021,"count":17},{"year":2022,"count":8},{"year":2023,"count":3},{"year":2024,"count":7},{"year":2025,"count":6},{"year":2026,"count":2}],"oa_status":"green","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3825681","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3825681","host_type":"repository"},{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201302805","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201302805","host_type":"publisher"},{"url":"https://doi.org/10.1002/anie.201302805","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23824625","host_type":"repository"},{"url":"http://europepmc.org/abstract/MED/23824625","host_type":"repository"}],"fields_of_study":["Asymmetric Synthesis and Catalysis","Advanced Synthetic Organic Chemistry","Chemical synthesis and alkaloids","Alkaloids","Carbon","Catalysis","Molecular Structure","Organometallic Compounds","Palladium","Stereoisomerism","Tryptamines"],"mesh_terms":["Alkaloids","Carbon","Catalysis","Organometallic Compounds","Palladium","Stereoisomerism","Tryptamines","Molecular Structure"],"keywords":["Stereocenter","Vicinal","Tsuji–Trost reaction","Enantioselective synthesis","Palladium","Catalysis","Chemistry","Alkylation","Stereochemistry","Quaternary carbon","Combinatorial chemistry","Organic chemistry","Asymmetric catalysis","alkaloids","Quaternary Stereocenters","Allylic Alkylation"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T17:10:25.609131Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}