{"doi":"10.1002/ange.202218427","title":"L‐Shaped Heterobidentate Imidazo[1,5‐<i>a</i>]pyridin‐3‐ylidene (N,C)‐Ligands for Oxidant‐Free Au<sup>I</sup>/Au<sup>III</sup> Catalysis","abstract":"Abstract In the last decade, major advances have been made in homogeneous gold catalysis. However, Au I /Au III catalytic cycle remains much less explored due to the reluctance of Au I to undergo oxidative addition and the stability of the Au III intermediate. Herein, we report activation of aryl halides at gold(I) enabled by NHC (NHC=N‐heterocyclic carbene) ligands through the development of a new class of L‐shaped heterobidentate ImPy (ImPy=imidazo[1,5‐a]pyridin‐3‐ylidene) N,C ligands that feature hemilabile character of the amino group in combination with strong σ‐donation of the carbene center in a rigid conformation, imposed by the ligand architecture. Detailed characterization and control studies reveal key ligand features for Au I /Au III redox cycle, wherein the hemilabile nitrogen is placed at the coordinating position of a rigid framework. Given the tremendous significance of homogeneous gold catalysis, we anticipate that this ligand platform will find widespread application.","journal":"Angewandte Chemie","year":2023,"id":387831,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.946,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1024634,"name":"Jihong Xu","orcid":"0000-0001-8659-5487","position":1,"is_corresponding":false},{"id":292008,"name":"Tongliang Zhou","orcid":"0000-0002-7334-7078","position":2,"is_corresponding":false},{"id":1024635,"name":"Yanhong Liu","orcid":"0000-0002-2567-420X","position":3,"is_corresponding":false},{"id":887037,"name":"Elwira Bisz","orcid":"0000-0002-7070-2468","position":4,"is_corresponding":false},{"id":887038,"name":"Błażej Dziuk","orcid":"0000-0003-1593-2719","position":5,"is_corresponding":false},{"id":641131,"name":"Roger A. Lalancette","orcid":"0000-0002-3470-532X","position":6,"is_corresponding":false},{"id":641132,"name":"Roman Szostak","orcid":"0000-0002-5436-7284","position":7,"is_corresponding":false},{"id":1024636,"name":"Dongju Zhang","orcid":"0000-0002-1819-3053","position":8,"is_corresponding":false},{"id":240705,"name":"Michal Szostak","orcid":"0000-0002-9650-9690","position":9,"is_corresponding":false},{"id":665132,"name":"Pengcheng Gao","orcid":"0000-0003-4266-0616","position":0,"is_corresponding":true}],"reference_count":110,"raw_metadata":null,"created_at":"2026-07-19T01:18:08.845494Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}