{"doi":"10.1002/ana.26513","title":"Outcomes in the Year After First‐Ever Ischemic Stroke in a Bi‐Ethnic Population","abstract":"OBJECTIVE: To investigate stroke outcomes at 3, 6, and 12 months post-stroke overall and by ethnicity in a population-based, longitudinal study. METHODS: First-ever ischemic strokes (2014-2019, n = 1,332) among Mexican American persons (n = 807) and non-Hispanic white persons (n = 525) were identified from the Brain Attack Surveillance in Corpus Christi Project. Data were collected from patient or proxy interviews (baseline, 3, 6, and 12 months post-stroke) and medical records, including functional (activities of daily living/instrumental activities of daily living score), neurological (National Institutes of Health Stroke Scale), cognitive (Modified Mini-Mental State Examination), and quality of life (QOL) outcomes (12-domain Stroke-specific Quality of Life scale). Outcome trajectories were analyzed using multivariable adjusted linear models, with generalized estimating equations to account for within-subject correlations; interactions between ethnicity and time were included to investigate ethnic differences in outcomes. RESULTS: The median age was 67 years (interquartile range 58,78), 48.5% were women, and 60.6% were Mexican American persons. For all outcomes, significant improvement was seen between 3 and 6 months (p < 0.05 for all), with stability between 6 and 12 months. Mexican American persons had significantly worse outcomes compared with non-Hispanic white persons at all time points (3, 6, and 12 months), with the exception of the National Institutes of Health Stroke Scale, which did not differ by ethnicity at 6 and 12 months, and the average change in outcomes did not vary significantly by ethnicity. INTERPRETATION: Outcomes were at their worst at 3 months post-stroke, and ethnic disparities were already present, suggesting the need for early assessment and strategies to improve outcomes and possibly reduce disparities. ANN NEUROL 2023;93:348-356.","journal":"Annals of Neurology","year":2022,"id":262399,"datarank":0.47260395072460626,"base_score":2.70805020110221,"endowment":2.70805020110221,"self_citation_contribution":0.40620753016533157,"citation_network_contribution":0.06639642055927468,"self_endowment_contribution":0.40620753016533157,"citer_contribution":0.06639642055927468,"corpus_percentile":59.70449446894098,"corpus_rank":5210,"citation_count":14,"citer_count":6,"citers_with_citation_signal":3,"citers_with_endowment":3,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.7195,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":369343,"name":"Devin L. Brown","orcid":"0000-0002-9815-3421","position":1,"is_corresponding":false},{"id":475606,"name":"Liming Dong","orcid":"0000-0003-1512-9424","position":2,"is_corresponding":false},{"id":366551,"name":"Darin B. Zahuranec","orcid":"0000-0002-9772-2469","position":3,"is_corresponding":false},{"id":917787,"name":"Madeline Kwicklis","orcid":"0000-0003-1720-1186","position":4,"is_corresponding":false},{"id":280662,"name":"Xu Shi","orcid":"0000-0001-8566-9552","position":5,"is_corresponding":false},{"id":369345,"name":"Erin Case","orcid":"0000-0002-4198-454X","position":6,"is_corresponding":false},{"id":437935,"name":"Melinda A. Smith","orcid":"0000-0002-7550-2959","position":7,"is_corresponding":false},{"id":788804,"name":"Morgan Campbell","orcid":"0009-0000-4659-4818","position":8,"is_corresponding":false},{"id":917788,"name":"Joseph Carrera","orcid":"0000-0003-2487-4506","position":9,"is_corresponding":false},{"id":366550,"name":"Lewis B. Morgenstern","orcid":"0000-0002-5787-592X","position":10,"is_corresponding":false},{"id":74974,"name":"Lynda D. Lisabeth","orcid":"0000-0001-5539-5933","position":0,"is_corresponding":true}],"reference_count":18,"raw_metadata":null,"created_at":"2026-07-19T00:26:20.717229Z","pmid":"36134521","pmcid":"PMC9892337","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}