{"doi":"10.1002/alz.70671","title":"Demographically adjusted normative data among Peruvians with diverse education levels for version 3 of the Alzheimer's Disease Centers’ neuropsychological test battery in the Uniform Data Set","abstract":"INTRODUCTION: Demographically adjusted norms are essential for interpreting cognitive tests, yet none exist in Peru for the Alzheimer's Disease Centers' (ADCs) neuropsychological test battery, especially among low-education populations. METHODS: We assessed 340 healthy adults (ages 43-79, 70% female), balanced by education level (0-6 years, n = 173; ≥ 7 years, n = 167). Participants completed the Uniform Data Set version 3 Neuropsychological Battery (UDS3-NB). Normative values were generated using linear regression with age, education, and sex as predictors. RESULTS: Education groups were matched for age (p = 0.970) and sex (p = 0.904). Neuropsychological measurements varied significantly between education groups, with education emerging as the primary influential factor across all measures, except semantic fluency: vegetables. DISCUSSION: This study provides comprehensive normative cognitive data for Peruvian adults across a range of education levels, which will assist in the more precise identification of cognitive impairments. Clinicians can determine individual z scores for each neuropsychological measure with the included calculator. HIGHLIGHTS: We developed demographically adjusted normative data and a z score calculator for the Uniform Data Set version 3 Neuropsychological Battery among Peruvian adults. Recruitment was balanced by education level (0-6 vs. ≥ 7 years) to reflect the diverse educational backgrounds in Peru. Education was the strongest predictor of performance across most cognitive tests, particularly for working memory/executive tasks. These normative data support more accurate cognitive assessments and dementia diagnoses in Peruvian populations.","journal":"Alzheimer s & Dementia","year":2025,"id":524494,"datarank":0.24948657869355279,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.008070891828437718,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.008070891828437718,"corpus_percentile":40.1175833526727,"corpus_rank":7742,"citation_count":4,"citer_count":2,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.8903,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1359883,"name":"Diego Bustamante‐Paytan","orcid":"0000-0002-1073-1961","position":1,"is_corresponding":false},{"id":1398544,"name":"María Fe Albujar Pereira","orcid":null,"position":2,"is_corresponding":false},{"id":922460,"name":"José Carlos Huilca","orcid":"0000-0001-5561-4702","position":3,"is_corresponding":false},{"id":1260157,"name":"Belén Custodio","orcid":"0009-0007-1445-7211","position":4,"is_corresponding":false},{"id":1260158,"name":"Katherine Agüero","orcid":"0000-0002-1137-1363","position":5,"is_corresponding":false},{"id":1360293,"name":"Graciet Verastegui","orcid":null,"position":6,"is_corresponding":false},{"id":1359884,"name":"Zadith Yauri","orcid":"0009-0000-8101-513X","position":7,"is_corresponding":false},{"id":1398545,"name":"Pamela Bartolo","orcid":null,"position":8,"is_corresponding":false},{"id":1398546,"name":"Daniela Bendezu","orcid":null,"position":9,"is_corresponding":false},{"id":262293,"name":"Rosa Montesinos","orcid":"0000-0002-9342-8756","position":10,"is_corresponding":false},{"id":262259,"name":"Nilton Custodio","orcid":"0000-0002-8025-3272","position":11,"is_corresponding":false},{"id":422722,"name":"Gregory L. Brown","orcid":"0000-0002-4013-8405","position":0,"is_corresponding":true}],"reference_count":37,"raw_metadata":null,"created_at":"2026-07-19T02:50:12.083054Z","pmid":"40987938","pmcid":"PMC12457076","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}