{"doi":"10.1002/alz.12296","title":"COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US","abstract":"INTRODUCTION: At present, there is limited data on the risks, disparity, and outcomes for COVID-19 in patients with dementia in the United States. METHODS: This is a retrospective case-control analysis of patient electronic health records (EHRs) of 61.9 million adult and senior patients (age ≥ 18 years) in the United States up to August 21, 2020. RESULTS: Patients with dementia were at increased risk for COVID-19 compared to patients without dementia (adjusted odds ratio [AOR]: 2.00 [95% confidence interval (CI), 1.94-2.06], P < .001), with the strongest effect for vascular dementia (AOR: 3.17 [95% CI, 2.97-3.37], P < .001), followed by presenile dementia (AOR: 2.62 [95% CI, 2.28-3.00], P < .001), Alzheimer's disease (AOR: 1.86 [95% CI, 1.77-1.96], P < .001), senile dementia (AOR: 1.99 [95% CI, 1.86-2.13], P < .001) and post-traumatic dementia (AOR: 1.67 [95% CI, 1.51-1.86] P < .001). Blacks with dementia had higher risk of COVID-19 than Whites (AOR: 2.86 [95% CI, 2.67-3.06], P < .001). The 6-month mortality and hospitalization risks in patients with dementia and COVID-19 were 20.99% and 59.26%, respectively. DISCUSSION: These findings highlight the need to protect patients with dementia as part of the strategy to control the COVID-19 pandemic.","journal":"Alzheimer s & Dementia","year":2021,"id":146008,"datarank":6.70939396407174,"base_score":5.616771097666572,"endowment":5.616771097666572,"self_citation_contribution":0.8425156646499858,"citation_network_contribution":5.866878299421755,"self_endowment_contribution":0.8425156646499858,"citer_contribution":5.866878299421755,"corpus_percentile":97.199659627137,"corpus_rank":363,"citation_count":274,"citer_count":100,"citers_with_citation_signal":100,"citers_with_endowment":100,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.6697,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":328946,"name":"Pamela B. Davis","orcid":"0000-0002-0013-8750","position":1,"is_corresponding":false},{"id":257969,"name":"Mark E. Gurney","orcid":"0000-0003-4901-3083","position":2,"is_corresponding":false},{"id":109147,"name":"Rong Xu","orcid":"0000-0003-3127-4795","position":3,"is_corresponding":false},{"id":109757,"name":"QuanQiu Wang","orcid":null,"position":0,"is_corresponding":true}],"reference_count":59,"raw_metadata":null,"created_at":"2026-07-18T23:42:18.947086Z","pmid":"33559975","pmcid":"PMC8014535","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}