{"doi":"10.1002/adhm.202302613","title":"E‐Suture: Mixed‐Conducting Suture for Medical Devices","abstract":"Modern implantable bioelectronics demand soft, biocompatible components that make robust, low-impedance connections with the body and circuit elements. Concurrently, such technologies must demonstrate high efficiency, with the ability to interface between the body's ionic and external electronic charge carriers. Here, a mixed-conducting suture, the e-suture, is presented. Composed of silk, the conducting polymer poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and insulating jacketing polymers,the resulting e-suture has mixed-conducting properties at the interface with biological tissue as well as effective insulation along its length. The e-suture can be mechanically integrated into electronics, enabling the acquisition of biopotentials such as electrocardiograms, electromyograms, and local field potentials (LFP). Chronic, in vivo acquisition of LFP with e-sutures remains stable for months with robust brain activity patterns. Furthermore, e-sutures can establish electrophoretic-based local drug delivery, potentially offering enhanced anatomical targeting and decreased side effects associated with systemic administration, while maintaining an electrically conducting interface for biopotential monitoring. E-sutures expand on the conventional role of sutures and wires by providing a soft, biocompatible, and mechanically sound structure that additionally has multifunctional capacity for sensing, stimulation, and drug delivery.","journal":"Advanced Healthcare Materials","year":2023,"id":354580,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9514,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":702336,"name":"Liang Ma","orcid":"0000-0003-3883-1902","position":1,"is_corresponding":false},{"id":1102149,"name":"D. Wiśniewski","orcid":"0000-0001-5405-1258","position":2,"is_corresponding":false},{"id":1102629,"name":"Shao Shan","orcid":null,"position":3,"is_corresponding":false},{"id":1102630,"name":"Brandon Schumacher","orcid":null,"position":4,"is_corresponding":false},{"id":1102631,"name":"Jose Lopez","orcid":null,"position":5,"is_corresponding":false},{"id":1102632,"name":"M. R. Kaspers","orcid":null,"position":6,"is_corresponding":false},{"id":350274,"name":"Zifang Zhao","orcid":"0000-0003-4145-4562","position":7,"is_corresponding":false},{"id":288725,"name":"Jennifer N. Gelinas","orcid":"0000-0002-1164-638X","position":8,"is_corresponding":false},{"id":288723,"name":"Dion Khodagholy","orcid":"0000-0003-0805-4612","position":9,"is_corresponding":false},{"id":350275,"name":"Onni J. Rauhala","orcid":"0000-0001-8964-5398","position":0,"is_corresponding":true}],"reference_count":48,"raw_metadata":null,"created_at":"2026-07-19T01:13:11.976628Z","pmid":"38150402","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}