{"doi":"10.1002/adhm.202102425","title":"Highly Precise, Continuous, Long‐Term Monitoring of Skin Electrical Resistance by Nanomesh Electrodes","abstract":"<jats:title>Abstract</jats:title><jats:p>The transepidermal water loss has been widely used as a method for directly evaluating the barrier function of the stratum corneum of the skin. However, transepidermal water loss could not be measured continuously for a long period of time, and there were no reports of continuous monitoring of skin barrier functions. Here, a method is reported to continuously monitor the skin electrical resistance by nanomesh electrodes for a long period of time while maintaining the natural skin condition that does not inhibit water evaporation. Simultaneous measurements of the skin electrical resistance by nanomesh electrodes and transepidermal water loss exhibits a linear fit with a high negative correlation. Furthermore, dynamics of skin physiological functions are successfully visualized by monitoring of the skin electrical resistance by nanomesh electrodes for 30 h in daily life.</jats:p>","journal":"Advanced Healthcare Materials","year":2022,"id":649696,"datarank":0.519860385419959,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.0,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":966708,"name":"Hiroshi Kawasaki","orcid":"0000-0002-2514-1497","position":1,"is_corresponding":false},{"id":867223,"name":"Sunghoon Lee","orcid":"0000-0002-8916-2035","position":2,"is_corresponding":false},{"id":1204360,"name":"Tomoyuki Yokota","orcid":"0000-0003-1546-8864","position":3,"is_corresponding":false},{"id":205358,"name":"Masayuki Amagai","orcid":"0000-0003-3314-7052","position":4,"is_corresponding":false},{"id":1013654,"name":"Takao Someya","orcid":"0000-0003-3051-1138","position":5,"is_corresponding":false},{"id":1693764,"name":"Akihito Miyamoto","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Highly Precise, Continuous, Long‐Term Monitoring of Skin Electrical Resistance by Nanomesh Electrodes","abstract":"<jats:title>Abstract</jats:title><jats:p>The transepidermal water loss has been widely used as a method for directly evaluating the barrier function of the stratum corneum of the skin. However, transepidermal water loss could not be measured continuously for a long period of time, and there were no reports of continuous monitoring of skin barrier functions. Here, a method is reported to continuously monitor the skin electrical resistance by nanomesh electrodes for a long period of time while maintaining the natural skin condition that does not inhibit water evaporation. Simultaneous measurements of the skin electrical resistance by nanomesh electrodes and transepidermal water loss exhibits a linear fit with a high negative correlation. Furthermore, dynamics of skin physiological functions are successfully visualized by monitoring of the skin electrical resistance by nanomesh electrodes for 30 h in daily life.</jats:p>","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34994099","pmcid":null,"openalex_id":"https://openalex.org/W4206510592","authors":[],"funders":[{"funder_name":"Accelerated Innovation Research Initiative Turning Top Science and Ideas into High-Impact Values","grant_id":"JPMJMI17F1","title":null}],"total_grants":1,"fwci":1.9828,"citation_percentile":0.85166149,"influential_citations":0,"citation_trend":[{"year":2022,"count":5},{"year":2023,"count":7},{"year":2024,"count":5},{"year":2025,"count":7},{"year":2026,"count":7}],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#am","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/adhm.202102425","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/adhm.202102425","host_type":"publisher"},{"url":"https://advanced.onlinelibrary.wiley.com/doi/am-pdf/10.1002/adhm.202102425","host_type":"publisher"},{"url":"https://advanced.onlinelibrary.wiley.com/doi/pdf/10.1002/adhm.202102425","host_type":"publisher"},{"url":"https://doi.org/10.1002/adhm.202102425","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34994099","host_type":"repository"}],"fields_of_study":["Advancements in Transdermal Drug Delivery","Advanced Sensor and Energy Harvesting Materials","Nanomaterials and Printing Technologies","Electric Impedance","Electrodes","Skin","Water","Water Loss, Insensible"],"mesh_terms":["Electrodes","Skin","Water","Water Loss, Insensible","Electric Impedance"],"keywords":["Nanomesh","Transepidermal water loss","Stratum corneum","Electrode","Materials science","Skin barrier","Electrical resistance and conductance","Biomedical engineering","Optoelectronics","Nanotechnology","Dermatology","Composite material","Medicine","Chemistry","Graphene","Pathology","Transepidermal Water Loss (Tewl)","Skin Electrical Resistance","Skin Sensors","Nanomesh Electrodes"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T04:10:19.660849Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}