{"doi":"10.1002/adfm.202005029","title":"Light: A Magical Tool for Controlled Drug Delivery","abstract":"Light is a particularly appealing tool for on-demand drug delivery due to its noninvasive nature, ease of application and exquisite temporal and spatial control. Great progress has been achieved in the development of novel light-driven drug delivery strategies with both breadth and depth. Light-controlled drug delivery platforms can be generally categorized into three groups: photochemical, photothermal, and photoisomerization-mediated therapies. Various advanced materials, such as metal nanoparticles, metal sulfides and oxides, metal-organic frameworks, carbon nanomaterials, upconversion nanoparticles, semiconductor nanoparticles, stimuli-responsive micelles, polymer- and liposome-based nanoparticles have been applied for light-stimulated drug delivery. In view of the increasing interest in on-demand targeted drug delivery, we review the development of light-responsive systems with a focus on recent advances, key limitations, and future directions.","journal":"Advanced Functional Materials","year":2020,"id":49025,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":306,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9525,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":235100,"name":"Hon Fai Chan","orcid":"0000-0003-0573-1251","position":1,"is_corresponding":false},{"id":235101,"name":"Bingyang Shi","orcid":"0000-0002-1043-3163","position":2,"is_corresponding":false},{"id":235102,"name":"Mingqiang Li","orcid":"0000-0002-5178-4138","position":3,"is_corresponding":false},{"id":235103,"name":"Kam W. Leong","orcid":"0000-0002-8133-4955","position":4,"is_corresponding":false},{"id":235099,"name":"Yu Tao","orcid":"0000-0001-5087-7474","position":0,"is_corresponding":true}],"reference_count":430,"raw_metadata":null,"created_at":"2026-07-18T20:36:25.163232Z","pmid":"34483808","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}