{"doi":"10.1002/9781119807704.ch11","title":"Emerging Non‐invasive Molecular Biomarkers for Early Cancer Detection","abstract":null,"journal":"Genomic and Epigenomic Biomarkers of Toxicology and Disease","year":2022,"id":684724,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":933932,"name":"Yingxue Zhang","orcid":"0000-0003-0698-0532","position":1,"is_corresponding":false},{"id":933933,"name":"Eid Alshammari","orcid":"0000-0002-8676-9480","position":2,"is_corresponding":false},{"id":151222,"name":"Zhe Yang","orcid":null,"position":3,"is_corresponding":false},{"id":934474,"name":"Jacob Sobota","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Emerging Non‐invasive Molecular Biomarkers for Early Cancer Detection","abstract":"Cancer is a heterogenous disease that has worsening survival rates as it progresses. Diagnosing cancer in its early stages is therefore critical to improving the survival rates of patients. The difficulties of early cancer diagnosis are now considerably eased as a result of emerging non-invasive biomarkers. An increasingly favored option of non-invasive diagnosis is the “liquid biopsy,” which can provide diagnostic and prognostic information at a level equal to or higher than that of tissue biopsy by analyzing bodily fluids. Multiple biomarkers are present in liquid biopsy samples that are emerging as promising non-invasive early diagnosis options. Nucleic acids such as circulating tumor DNA and micro RNA are increasingly investigated as providers of information on an individual's state of disease. Classes of extracellular vesicles such as exosomes can also offer diagnostic information through their content and through the composition of their membranes. Here we review ongoing research that yields emergent non-invasive biomarkers in early cancer diagnosis.","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":null,"pmcid":null,"openalex_id":"https://openalex.org/W4229027233","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2023,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://doi.org/10.1002/9781119807704.ch11","host_type":""}],"fields_of_study":["Extracellular vesicles in disease","Cancer Genomics and Diagnostics","Cancer-related molecular mechanisms research"],"mesh_terms":[],"keywords":["Liquid biopsy","Extracellular vesicles","Cancer","Disease","Biomarker","Biopsy","Microvesicles","Cancer biomarkers","Diagnostic biomarker","Medicine","Pathology","Biology","Internal medicine","microRNA","Gene"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T14:53:02.539392Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}