{"doi":"10.1002/9781119423492.ch21","title":"Eosinophilic esophagitis","abstract":null,"journal":"Practical Pediatric Gastrointestinal Endoscopy","year":2021,"id":611060,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":233046,"name":"Glenn T. Furuta","orcid":"0000-0003-3262-3571","position":1,"is_corresponding":false},{"id":1571343,"name":"Robert E. Kramer","orcid":null,"position":2,"is_corresponding":false},{"id":663135,"name":"Calies Menard‐Katcher","orcid":"0000-0003-2810-8171","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Eosinophilic esophagitis","abstract":"Over the last decade, eosinophilic esophagitis (EoE) has emerged as one of the most common causes of food impaction in children and adults. The diagnosis of EoE depends on the presence of symptoms and an abnormal esophageal biopsy that contains greater than 15 eosinophils per high-power field (HPF). While there are several efforts to introduce less invasive methods of monitoring of mucosal inflammation once EoE is diagnosed, esophageal endoscopy continues to be essential to the diagnosis and management of EoE. To date, mucosal eosinophil enumeration has served as a biomarker for disease activity and therapeutic success. Since the esophageal biopsy represents less than 1% of the total surface area and counting eosinophils can be fraught with intraobserver variability, alternative methods have been sought. One of these focuses on the gross appearance of the esophageal mucosa and encompasses endoscopic features presently associated with EoE.","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W4241134525","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2024,"count":1},{"year":2025,"count":1}],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1.1","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781119423492.ch21","host_type":"publisher"},{"url":"https://doi.org/10.1002/9781119423492.ch21","host_type":""}],"fields_of_study":["Eosinophilic Esophagitis","Eosinophilic Disorders and Syndromes"],"mesh_terms":[],"keywords":["Eosinophilic esophagitis","Medicine","High-power field","Biopsy","Eosinophil","Gastroenterology","Esophagus","Esophagitis","Endoscopy","Internal medicine","Disease","Pathology","Reflux","Asthma","Immunohistochemistry"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-01T15:03:00.331469Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}