{"doi":"10.1002/9780470101001.hcn052","title":"Regulation of Adult Neurogenesis","abstract":"<jats:title>Abstract</jats:title>\n          <jats:p>Several neuronal populations in the mammalian central nervous system (CNS) continue to be generated from dividing precursor cells well into adulthood. A large number of factors regulating adult neurogenesis have now been identified, including specific experiences, as well as hormones, neurotransmitters, and growth factors. Distinct factors control neuronal precursor proliferation and survival of the young neurons, and distinct, though somewhat overlapping, factors control these processes in the dentate gyrus and olfactory bulb. Although no coherent picture has emerged to connect all of the regulatory factors, there appears to be a direct relationship between the ability to increase neurogenesis in the dentate gyrus and anti‐depressant properties, either in humans or animal models. This review discusses the large number of factors currently known to regulate cell proliferation and survival of young neurons in the dentate gyrus and olfactory bulb.</jats:p>","journal":"Handbook of Contemporary Neuropharmacology","year":2007,"id":20591,"datarank":0.8478804988568084,"base_score":2.639057329615259,"endowment":2.639057329615259,"self_citation_contribution":0.3958585994422889,"citation_network_contribution":0.4520218994145195,"self_endowment_contribution":0.3958585994422889,"citer_contribution":0.4520218994145195,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":13,"citers_with_citation_signal":13,"citers_with_endowment":13,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":135557,"name":"Heather A. Cameron","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":2.639057329615259,"endowment":2.639057329615259,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21071399","pmcid":null,"openalex_id":"https://openalex.org/W1582992535","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":2,"citation_trend":[{"year":2012,"count":6},{"year":2015,"count":2},{"year":2016,"count":1}],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1.1","oa_locations":[{"url":"http://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F9780470101001.hcn052","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/9780470101001.hcn052","host_type":"publisher"},{"url":"https://doi.org/10.1002/9780470101001.hcn052","host_type":""}],"fields_of_study":["Neurogenesis and neuroplasticity mechanisms","Nerve injury and regeneration","Axon Guidance and Neuronal Signaling","Biology","Medicine"],"mesh_terms":[],"keywords":["Neurogenesis","Dentate gyrus","Olfactory bulb","Neuroscience","Biology","Central nervous system"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-06T02:38:22.026958Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}