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Moreover, designed protein assemblies can implement symmetry similar to the viral capsids, while, on the other hand, single‐chain pseudosymmetric designs can address each position independently. Recently, the design is expanding towards the introduction of new functions into designed proteins, and we may soon be able to design molecular machines.</jats:p>","journal":"FEBS Letters","year":2020,"id":592754,"datarank":0.8864702238360587,"base_score":3.332204510175204,"endowment":3.332204510175204,"self_citation_contribution":0.49983067652628066,"citation_network_contribution":0.386639547309778,"self_endowment_contribution":0.49983067652628066,"citer_contribution":0.386639547309778,"corpus_percentile":null,"corpus_rank":null,"citation_count":27,"citer_count":26,"citers_with_citation_signal":17,"citers_with_endowment":17,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1516908,"name":"Tamara Šmidlehner","orcid":null,"position":1,"is_corresponding":false},{"id":41049,"name":"Roman Jerala","orcid":"0000-0002-6337-5251","position":2,"is_corresponding":false},{"id":1383599,"name":"Weijun Zhou","orcid":"0009-0001-8352-8200","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Synthetic biology principles for the design of protein with novel structures and functions","abstract":"<jats:p>Nature provides a large number of functional proteins that evolved during billions of years of evolution. 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