{"doi":"10.1002/047001153x.g406119","title":"Protein structure analysis and prediction","abstract":"<jats:title>Abstract</jats:title>\n          <jats:p>The comparative analysis of protein sequence and structure has provided great insights into the function and evolution of proteins. This approach relies on both sequence comparison and structure comparison with the latter, giving the deepest view on distant relationships, especially when just the overall fold of the proteins is compared. The establishment of correlation between sequence features and structural features can allow structure to be predicted from sequence. This can range from isolated fragments of structure (sometimes called motifs) to the overall fold of the proteins. With the progress in the determination of genomes and many new structures from structural genomics programs, there is an increasing wealth of data for comparative analysis.</jats:p>","journal":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics","year":2005,"id":684503,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":320054,"name":"William R. Taylor","orcid":"0000-0003-4060-4098","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Protein structure analysis and prediction","abstract":"<jats:title>Abstract</jats:title>\n          <jats:p>The comparative analysis of protein sequence and structure has provided great insights into the function and evolution of proteins. This approach relies on both sequence comparison and structure comparison with the latter, giving the deepest view on distant relationships, especially when just the overall fold of the proteins is compared. The establishment of correlation between sequence features and structural features can allow structure to be predicted from sequence. This can range from isolated fragments of structure (sometimes called motifs) to the overall fold of the proteins. With the progress in the determination of genomes and many new structures from structural genomics programs, there is an increasing wealth of data for comparative analysis.</jats:p>","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W1831126377","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2024,"count":1}],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1.1","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/047001153X.g406119","host_type":"publisher"},{"url":"https://doi.org/10.1002/047001153x.g406119","host_type":"journal"}],"fields_of_study":["Protein Structure and Dynamics","Enzyme Structure and Function","Microbial Metabolic Engineering and Bioproduction"],"mesh_terms":[],"keywords":["Structural genomics","Computational biology","Sequence (biology)","Protein structure","Sequence analysis","Protein structure database","Protein structure prediction","Protein function prediction","Biology","Sequence alignment","Protein sequencing","Evolutionary biology","Protein function","Genetics","Peptide sequence","Sequence database","Gene"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T14:17:46.274469Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}