{"doi":"10.1001/jamanetworkopen.2024.42140","title":"Meal Timing Interventions for Weight Loss and Metabolic Health—What Does the Evidence Tell Us So Far?","abstract":"Obesity is a serious health issue in the US, with a prevalence of 40% in adults. 1 Calorie restriction through dietary modification remains the foundation of obesity management; however, traditional dietary modification through low-calorie diets is resource-heavy and shows poor long-term adherence, resulting in subsequent weight regain. 2 Alternative lifestyle interventions include meal timing strategies, which consider the interplay between food intake and circadian biology.Meal timing strategies include time-restricted eating (TRE), meal frequency, and 24-hour caloric distribution.All of these are low-cost and easy-to-adopt approaches that may serve as treatment and prevention of metabolic diseases (eg, type 2 diabetes and hypertension).In this systematic review and meta-analysis, Liu et al 3 aimed to evaluate the existing evidence and determine the long-term (12 weeks) associations of meal timing strategies with anthropometrics and metabolic outcomes in adults with and without metabolic disease.Study selection included randomized clinical trials (RCTs) that enrolled adults aged 18 years or older, evaluated within-day meal timing patterns for 12 weeks or longer, and reported anthropometric measures.The main outcome was weight change (kilograms), and secondary outcomes included lean and/or fat-free mass, waist circumference, hemoglobin A 1c level, fasting glucose level, low-density lipoprotein level, systolic and diastolic blood pressure,","journal":"JAMA Network Open","year":2024,"id":505609,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9508,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":407407,"name":"Emily N. C. Manoogian","orcid":"0000-0001-9718-9310","position":1,"is_corresponding":false},{"id":107066,"name":"Blandine Laferrère","orcid":"0000-0001-8255-3175","position":2,"is_corresponding":false},{"id":1073548,"name":"Collin J. Popp","orcid":"0000-0002-5680-8784","position":0,"is_corresponding":true}],"reference_count":8,"raw_metadata":null,"created_at":"2026-07-19T02:10:47.170978Z","pmid":"39485356","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}