{"doi":"10.1001/jama.270.24.2957","title":"A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study","abstract":"<h4>Objective</h4>To develop and validate a new Simplified Acute Physiology Score, the SAPS II, from a large sample of surgical and medical patients, and to provide a method to convert the score to a probability of hospital mortality.<h4>Design and setting</h4>The SAPS II and the probability of hospital mortality were developed and validated using data from consecutive admissions to 137 adult medical and/or surgical intensive care units in 12 countries.<h4>Patients</h4>The 13,152 patients were randomly divided into developmental (65%) and validation (35%) samples. Patients younger than 18 years, burn patients, coronary care patients, and cardiac surgery patients were excluded.<h4>Outcome measure</h4>Vital status at hospital discharge.<h4>Results</h4>The SAPS II includes only 17 variables: 12 physiology variables, age, type of admission (scheduled surgical, unscheduled surgical, or medical), and three underlying disease variables (acquired immunodeficiency syndrome, metastatic cancer, and hematologic malignancy). Goodness-of-fit tests indicated that the model performed well in the developmental sample and validated well in an independent sample of patients (P = .883 and P = .104 in the developmental and validation samples, respectively). The area under the receiver operating characteristic curve was 0.88 in the developmental sample and 0.86 in the validation sample.<h4>Conclusion</h4>The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis. This is a starting point for future evaluation of the efficiency of intensive care units.","journal":"JAMA: The Journal of the American Medical Association","year":1993,"id":492,"datarank":34.25369190328232,"base_score":8.949884285777994,"endowment":8.949884285777994,"self_citation_contribution":1.3424826428666994,"citation_network_contribution":32.911209260415625,"self_endowment_contribution":1.3424826428666994,"citer_contribution":32.911209260415625,"corpus_percentile":99.4,"corpus_rank":1193,"citation_count":7706,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":0,"is_dataset":false,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"1993-12-22","authors":[{"id":4870,"name":"J. R. Le Gall","orcid":"0009-0009-6353-2841","position":1,"is_corresponding":false},{"id":4869,"name":"Jean-Roger Le Gall","orcid":null,"position":0,"is_corresponding":true}],"reference_count":21,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-03-01T18:20:47.508186Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}